The incidence goes up to 9% in patients older than 50 years of age. ductal, lobular, tubular, and medullary) are sometimes diagnosed as a result of nipple discharge.Special attention should be given to papillary carcinoma, despite it being a rare malignancy ( The appropriate treatment should be based on the specific condition causing the abnormal nipple discharge.Nipple discharge is defined as fluid that comes out spontaneously from the nipple.

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Fibrocystic Breast Changes: Fibrocystic changes may produce a serous or light green and often multiductal discharge. Plasma Cell Mastitis: It is a rare type of chronic mastitis usually found in multiparous women.

It may lead to nipple inversion and may present with serosanguineous and thick nipple discharge.

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The breast is a secretory gland that responds to the stimulation of different hormones, including estrogen and progesterone.

These hormones are responsible for controlling breast development during puberty.

Up to 60% of nipple discharges associated with ductal ectasia containing bacteria.

Ductal ectasia does not indicate a predisposition to cancer.

Estrogen promotes the growth of the ducts in the breast, whereas progesterone helps in the development of the secretory cells.

The functional unit of the breast is called the terminal duct lobular unit (TDLU).

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